Fertility
What should a fertility workup include with endometriosis?
The short answer
A fertility workup with endometriosis typically includes ovarian reserve testing, pelvic ultrasound, ovulation checks, tubal testing, and semen analysis. MRI and other tests may be added based on symptoms, history, and initial findings.
A fertility workup with known or suspected endometriosis evaluates egg supply, ovulation, sperm, and pelvic anatomy, including whether endometriosis or adenomyosis may affect fertility through inflammation, adhesions, or distortion that interferes with egg pickup or implantation. We begin by reviewing cycle patterns, pain, bowel and bladder symptoms, prior pregnancies or losses, past surgeries, and previous results to target testing and avoid unnecessary repetition.
Core tests often include ovarian reserve assessment with AMH bloodwork and an antral follicle count to estimate egg supply, high-quality transvaginal ultrasound to assess the uterus and ovaries for endometriomas, adenomyosis, and other conditions, and sometimes expertly interpreted MRI to map suspected deep disease. Other testing assesses hormone levels, ovulation timing, the uterine cavity, and whether the fallopian tubes are open using contrast-based imaging such as HyCoSy, alongside a partner’s semen analysis because male-factor issues are common and can change the plan.
In selected cases, we also evaluate thyroid dysfunction, PCOS patterns, autoimmune overlap, or other whole-body factors that may complicate fertility, mimic symptoms, or amplify inflammation. HyCoSy checks tubal openness rather than reliably detecting endometriosis, and imaging and labs can inform suspicion without excluding disease when normal; when surgery is performed, tissue examination can confirm endometriosis, although biopsy results depend on sampling and surgical expertise.
We use the findings and your timeline to weigh timed intercourse, IUI, other fertility treatment, or surgical evaluation, including whether excision could help when endometriosis-related anatomy is a barrier. If you’d like, you can schedule a consultation with our team to review your records, identify any missing tests, interpret results, and plan efficient next steps for evaluation or fertility-focused care.
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Worried About Fertility and Endometriosis?
Our specialists understand how endometriosis can impact your fertility. We offer thorough evaluations to assess egg supply and pelvic health to guide your treatment options.
Questions people ask next
All fertility questionsWhat should I ask about endometriosis-related infertility?
Ask for a plan that specifically evaluates endometriosis or adenomyosis, including imaging, whether your tubes are open, and ovarian reserve. Ask how treatments affect your timeline, when an excision-focused surgical evaluation makes sense, and how pain care can support your fertility goals.
Do endometriomas affect fertility or ovarian reserve?
Yes, endometriomas can affect fertility and may be associated with lower ovarian reserve in some patients. Surgery, especially repeat cyst surgery, can also affect ovarian reserve because healthy ovarian tissue can be removed or its blood supply altered.
How does endometriosis affect fertility, and when to seek help?
Endometriosis can affect fertility through inflammation and scarring, but many people do conceive. In general, evaluation is recommended after 12 months of trying without success, or 6 months if you’re 35 or older; earlier evaluation is reasonable with severe pain or other risk factors.
Can an HSG detect endometriosis?
An HSG does not reliably detect endometriosis, as most lesions are in areas it cannot show. It checks the uterine cavity and whether the fallopian tubes are open, and can sometimes hint at related problems like tubal blockage or scarring.
Further reading
Making a Fertility Plan: Working with Your Endometriosis Care Team
Learn how to create a patient-centered fertility plan with your endometriosis care team, addressing symptoms, treatment, and desired timelines.
How Endometriosis Contributes to Infertility
How endometriosis leads to infertility: pathogenesis; effects on gametes, tubes, and endometrium; and treatments (expectant care, surgery, and ART).
Surgery and IVF: When Are They Right for Endometriosis?
Explore when surgery or IVF is best for endometriosis. Understand the decision-making process and what to consider for fertility and health.






