Fertility
Can adenomyosis cause miscarriage?
The short answer
Adenomyosis may contribute to miscarriage for some patients, but many people with adenomyosis have healthy pregnancies. Changes in the uterine muscle and environment may affect implantation and early placental development, and risk varies from person to person.
Adenomyosis can be associated with a higher risk of pregnancy complications, and it may contribute to miscarriage for some patients. But it’s not a guarantee, and many people with adenomyosis go on to have healthy pregnancies. It can matter because adenomyosis changes the uterine muscle and uterine environment, which may affect implantation and early placental development through inflammation and abnormal uterine contractions.
Risk isn’t the same for everyone. Outcomes often depend on the pattern of disease (focal adenomyoma versus diffuse adenomyosis), how much of the uterine wall/junctional zone is affected, and whether adenomyosis overlaps with endometriosis. This overlap is common and can compound fertility and pregnancy challenges. If you’ve experienced infertility, recurrent pregnancy loss, or repeated implantation failure, our team can help evaluate whether adenomyosis and coexisting endometriosis may be part of the picture and walk you through fertility-sparing options, including when surgery to remove a focal adenomyoma may be realistic versus when other approaches make more sense.
Where to go from here
Understand it, compare it with what you're feeling, then talk it through with us.
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Worried About Adenomyosis & Pregnancy?
We understand the concerns around adenomyosis and miscarriage risk. Our specialists can help evaluate your condition and support your fertility journey with personalized care.
Questions people ask next
All fertility questionsCan adenomyosis affect fertility or pregnancy?
Yes, adenomyosis can affect fertility and pregnancy, although not everyone will struggle to conceive. It may interfere with implantation and is associated with higher risks of miscarriage and preterm birth, especially with more diffuse disease.
Can focal adenomyosis affect fertility or miscarriage risk?
Yes, focal adenomyosis can affect fertility and miscarriage risk, especially when a lesion distorts the uterine cavity or interferes with implantation. Not all focal adenomyosis behaves the same: smaller nodules farther from the cavity may have less impact.
Does diffuse adenomyosis affect fertility and miscarriage risk?
Diffuse adenomyosis can affect fertility by changing uterine contractions and the environment where an embryo implants. For some patients, this can contribute to difficulty conceiving and may be associated with a higher risk of early miscarriage.
Further reading
Adenomyosis, Endometriosis, and Pregnancy: What Patients Need to Know
Explore how adenomyosis affects pregnancy and fertility with endometriosis. Get trusted research insights and advice for your care team.
Adenomyosis and Fertility: What Patients Need to Know
Explore how adenomyosis affects fertility. Learn about symptoms, research, and treatment options for better reproductive health.
Adenomyosis Pregnancy Success Rate With Fertility-Sparing Treatment
Explore adenomyosis pregnancy success rates after fertility-sparing treatment, including symptom relief, treatment choices, and pregnancy risks.






