Fertility
When should I get a miscarriage workup, and what is typically checked?
The short answer
A workup is often recommended after two consecutive first-trimester miscarriages or any second-trimester loss. Typical checks include the uterine cavity, antiphospholipid antibodies and thyroid function, with genetic testing in some situations.
A recurrent pregnancy loss evaluation is often recommended after two consecutive first-trimester miscarriages, or after any second-trimester loss. After a single early loss, many patients don’t need a full workup right away, but if there are additional risk factors or a complex history, we may recommend evaluating sooner.
A typical workup focuses on the most common, actionable causes. This often includes assessing the uterine cavity for issues such as a septum, fibroids, or polyps; checking labs such as antiphospholipid antibodies and thyroid function; and, in some situations, genetic testing such as parental karyotypes. More extensive clotting (thrombophilia) testing is usually reserved for select cases based on your history, and our team can help tailor an evaluation plan to your specific pattern of loss and symptoms.
Where to go from here
Understand it, compare it with what you're feeling, then talk it through with us.
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Concerned About Recurrent Miscarriages?
Our specialists understand how difficult pregnancy loss can be and offer thorough evaluations to identify causes. We focus on actionable factors to help you build a path toward a healthy pregnancy.
Questions people ask next
All fertility questionsWhat tests are done after two miscarriages with endometriosis?
After two miscarriages with endometriosis, we typically review your history and use pelvic imaging, often ultrasound and, when helpful, MRI. We may also evaluate thyroid function and other hormonal factors, and consider autoimmune overlap when symptoms or history point that way.
What should a fertility workup include with endometriosis?
A fertility workup with endometriosis typically includes ovarian reserve testing, pelvic ultrasound, ovulation checks, tubal testing, and semen analysis. MRI and other tests may be added based on symptoms, history, and initial findings.
Further reading
Endometriosis and Miscarriage: What Research Suggests
Learn how endometriosis may affect miscarriage risk, the roles of inflammation, hormones, and surgery, what current studies show, and ways to manage fertility.
Adenomyosis Pregnancy Success Rate With Fertility-Sparing Treatment
Explore adenomyosis pregnancy success rates after fertility-sparing treatment, including symptom relief, treatment choices, and pregnancy risks.





