
Getting Ready for Endometriosis Surgery: A Week‑by‑Week Guide
A logistics-focused countdown for endometriosis surgery preparation

You’ve got a surgery date on the calendar. Now the questions get very practical: What do I do this week? What needs to be scheduled? Which meds do I stop—and when? What should I buy, pack, and set up at home?
This guide stays strictly in the logistics lane—the operational “how-to” of how to prepare for endometriosis surgery and other minimally invasive gynecologic procedures (including some adenomyosis surgeries). It pulls together what multiple recent studies show about perioperative best practices—especially Enhanced Recovery After Surgery (ERAS) pathways—and adds the real-world steps patients most often need at the 1‑month and 1‑week marks.
If you’re a patient here at Lotus, and are looking for the full clinical picture (what happens during surgery, recovery timelines, and symptom expectations), login to your patient portal and browse the Surgery Prep module.
First, one rule that overrides everything
Your surgeon/anesthesia team’s written instructions win. ERAS pathways and medication guidance can vary by hospital, your health history, and what’s planned in the OR. Use this article as a checklist generator—then confirm specifics with your team.
A quick note on ERAS: across minimally invasive gynecologic surgeries, ERAS-style care is consistently linked with less pain, lower opioid needs, earlier eating/walking, and shorter hospital stay in many settings. Research also suggests outcomes are best when more ERAS elements are actually followed (higher “compliance” correlates with fewer complications and higher satisfaction). So: this isn’t just about what you do—the system matters too, and it’s worth asking if your hospital uses an ERAS pathway.
4–6 weeks out: Set the foundation (paperwork, health optimization, travel)
This is the “make time work for you” window—when you can fix problems before they become last-minute cancellations.
Medical clearance and pre-op testing
Depending on your age, symptoms, and medical history, your team may order labs (often CBC/iron studies), pregnancy testing (if applicable), and sometimes an EKG or other testing.
If you’ve had heavy bleeding (common with adenomyosis and sometimes endometriosis), ask early about anemia screening and correction. Even if your surgery is minimally invasive, going in with low iron can make recovery harder.
Imaging and records (especially if you’re traveling or changing surgeons)
If you’re still in the “final mapping” stage—especially for deep endometriosis—ask whether you need a specialist endometriosis ultrasound or MRI (and whether it must be done at a specific center). International survey data suggest ultrasound is widely used before surgery, but access and expertise can be concentrated in certain centers, and many clinicians report patients may not reliably get “specialist” imaging everywhere. Translation: if your prior ultrasound was “normal,” that may not be the same as a targeted endometriosis scan—worth clarifying now, not a week before surgery.
Travel and lodging (if you’re flying in)
If you’re traveling for care, book with recovery in mind:
- Lodging close to the hospital for the first 1–3 nights if same-day discharge is possible
- Flexible change/cancel options
- A plan for prescriptions (some hospitals send e-prescriptions to local pharmacies only)
Dental work timing (yes, really)
If you need dental work, try to complete it well before surgery when possible. The goal is to avoid last-minute infections, antibiotics, or inflammation close to your operation date. (Your surgeon can give a preferred window.)
Start the “ERAS conversation” early
Ask: “Do you use an ERAS pathway for laparoscopic surgery?”
Why this matters: in multiple gynecologic surgery studies, ERAS is associated with earlier return of bowel function, shorter catheter time, shorter length of stay, and sometimes lower costs—but benefits track with how consistently the pathway is followed. If your hospital uses ERAS, request a written patient handout so you can plan meals, rides, and supplies accordingly.
1–2 weeks out: Medication and supplement plan (the part that trips people up)
This is the most important window for endometriosis surgery preparation mistakes—because stopping (or continuing) the wrong thing can increase bleeding risk, interact with anesthesia, or cause day-of-surgery delays.
Build your personal “stop/continue” list
Send your team a complete list (photo is fine) of:
- Prescriptions
- OTC meds (including ibuprofen/naproxen/aspirin)
- Supplements (especially herbals)
- Hormones/birth control
- Weight-loss/diabetes injections and pills (including GLP‑1 drugs)
Then ask for explicit dates: “My surgery is on ___; what is my last dose of each medication?”
NSAIDs, aspirin, and blood thinners
Many surgeons ask patients to stop NSAIDs (like ibuprofen/naproxen) and aspirin ahead of time because they can affect bleeding—but timing varies based on your situation and why you take them.
If you take a prescribed blood thinner (or even a daily aspirin for a medical reason), do not self-stop. You need a coordinated plan (sometimes called a “bridge” plan).
Hormones and birth control
Whether to stop hormonal contraception or other hormones depends on your clot risk, the type of surgery, and your goals (symptom control, contraception, cycle timing). Some people are told to continue; others are told to stop. This is a “surgeon + anesthesia + your prescriber” decision—get it in writing.
Herbal supplements (common culprits)
Many herbals can affect bleeding, blood pressure, or sedation. If you take any, assume they need review. When in doubt: list everything and ask your surgeon for a stop date.
Questions About Preparing for Your Surgery?
Our specialists are here to help you understand your condition and explore your treatment options.
Talk to Our TeamGLP‑1 medications (semaglutide, tirzepatide, etc.): the anesthesia issue patients aren’t being told clearly
If you take a GLP‑1 receptor agonist (or GLP‑1/GIP medication) for diabetes or weight management, bring it up early—even if your surgery isn’t GI-related.
Plain-language why this matters: these medications can slow stomach emptying, meaning your stomach may still contain food/liquid despite standard fasting. That raises concern for regurgitation/aspiration around anesthesia.
Recent evidence in an elective endoscopy trial found that continuing GLP‑1/GLP‑1+GIP therapy (vs holding one dose) led to a much higher rate of unexpected residual stomach contents significant enough to prevent completing the procedure—even though patients followed usual instructions. Notably, people with clinically significant residual contents often did not have warning symptoms that day, so “I feel fine” isn’t a reliable safety check. A broader anesthesia-focused narrative review also describes evolving guidance and supports an individualized, risk-adapted plan based on symptoms, dose escalation phase, comorbidities, and procedure type—sometimes including diet modification, strict fasting, and selective gastric ultrasound.
What you should do (logistics):
- Tell anesthesia exactly which GLP‑1 drug you take, the dose, and when your last dose is scheduled.
- Ask: “Should I hold a dose? For how long?” and “Do you want a clear-liquid plan the day before?”
- Do not stop it on your own—your diabetes/weight prescriber may need to coordinate alternatives.
The week of surgery: Home setup, prescriptions, and “day-after” planning
This is when ERAS details (early walking, earlier eating, discharge timing) intersect with real life—transportation, food, and who’s helping you.
Confirm your ride and your first 24 hours of help
Many centers require:
- A responsible adult (18+) to drive you home
- A 24-hour companion after anesthesia (sometimes mandatory for outpatient surgery)
Lock this down early. If you don’t have someone local, tell the clinic now—social work or patient services may have options.
Arrange leave, childcare, and pet care
Even with minimally invasive approaches and ERAS, you may have lifting restrictions and fatigue. Plan for:
- Child pickup/dropoff
- Pet feeding/walking
- Backup coverage if you need an extra recovery day
Fill prescriptions before surgery (not on the way home)
ERAS pathways often reduce opioid use and emphasize multimodal pain control, but you still may be prescribed several meds (pain, nausea, bowel regimen). Multiple studies show ERAS is linked with less pain and fewer opioids overall, yet some experts caution that pain can be undertreated if plans are too rigid—especially for people with chronic pelvic pain.
Logistics move: ask your team to send discharge meds in advance when possible, and pick them up 1–3 days pre-op.
Stock your kitchen for “easy GI recovery”
ERAS research in benign gynecologic laparoscopy associates these pathways with faster bowel recovery (earlier gas/bowel movement), especially when early feeding and mobilization are used. Your job is to make that feasible:
Choose a small list of low-effort foods you tolerate well (your team may specify low-fiber/low-residue early on). Also buy:
- A stool softener/laxative if your discharge plan includes it
- Electrolyte drinks if allowed
- Simple protein options
Set up where you’ll actually sleep
Prepare a “recovery nest”:
- Phone charger within reach
- A small pillow for the car ride/abdominal bracing
- Nightstand meds/water
- A clear walking path (because early walking is often part of ERAS)
The last 48 hours: Follow the protocol (diet, skin prep, packing)
This is where you stop improvising and start executing the written plan.
Diet instructions: clear liquids, bowel prep, nutrition drinks
Your instructions may include any combination of:
- Clear-liquid window
- Bowel prep (varies widely; not everyone needs it)
- Carbohydrate/nutrition drinks (common in ERAS pathways)
- Specific fasting cutoffs for solids vs clear liquids
One gynecologic ERAS study specifically included practical measures like shorter fasting and earlier feeding and found better short-term recovery markers compared with conventional care. That said, your exact surgery (and whether bowel work might be involved) can change the plan—follow your surgeon’s version.
Skin prep (CHG showers) if provided
If you’re given chlorhexidine (CHG) soap/wipes, use them exactly as directed. Don’t add extra products that can irritate skin.
What to pack—and what to leave at home
Pack light, but purposefully:
- ID/insurance, device charger
- A list of meds/allergies
- Loose high-waist clothing
- Pads (spotting happens; tampons usually avoided initially)
- Glasses case (avoid contact hassle)
Leave valuables at home.
Practical takeaways: Questions to ask your PA (or surgeon/anesthesia team)
- “Do you use an ERAS pathway for my procedure—and can I have the patient checklist?”
- “Is my planned surgery outpatient/same-day, and what would make me stay overnight?”
- “Exactly when do I stop: NSAIDs, aspirin, blood thinners, herbals, and hormones?”
- “I take a GLP‑1 medication (name/dose). Should I hold it? Do you want a clear-liquid day before?”
- “What time can I drink clear liquids? What time do I stop everything by mouth?”
- “Will I have a catheter, and when does it come out?”
- “Can my discharge prescriptions be sent now so I can pick them up before surgery?”
- “Who do I call after hours if I’m worried?” (This matters—some ERAS programs shorten stays safely, but patients may need clearer post-discharge support to avoid unnecessary urgent visits.)
What we still don’t know (and why your plan may differ)
Even though ERAS is consistently linked with better short-term recovery markers in minimally invasive gynecologic surgery, real-world pathways vary: hospitals don’t all use the same protocol, adherence differs, and long-term outcomes are less consistently measured. Medication guidance—especially for GLP‑1 drugs—is also evolving as newer trials and consensus statements refine what’s safest for different procedures and patient risk profiles.
That’s why the best “pre-op checklist” is the one customized to your surgery, your medications, and your facility—and why getting your instructions early (then following them precisely) is one of the most powerful things you can do to protect your surgery date and your recovery.
References
Ortiz Vazquez, Londoño Victoria, Castillo López et al.. Minimally Invasive Gynecologic Surgery and Enhanced Recovery and Outcomes: A Literature Review. Cureus. 2025. PMID: 40568263 PMCID: PMC12188281
Nuermanguli, Jing, JiangYing et al.. Application of enhanced recovery after surgery in perioperative management of patients undergoing laparoscopic surgery for benign gynecological conditions. Medicine. 2025. PMID: 40696632 PMCID: PMC12282710
. Global trends in the uptake of specialist diagnostic ultrasound and MRI scans for endometriosis: An international cross‐sectional survey. International Journal of Gynaecology and Obstetrics. 2025. PMID: 41235636 PMCID: PMC12724021
Wang, Yang, Guo et al.. Tunnel method in laparoscopic single-position nephroureterectomy for women: preserving the uterine round ligament during distal ureter management and bladder cuff excision. Frontiers in Surgery. 2026. PMID: 41646644 PMCID: PMC12868241
Ahmad, Garg, Jacobs et al.. Holding vs Continuing GLP-1/GIP Agonists Before Upper Endoscopy. JAMA Internal Medicine. 2026. PMID: 41837981 PMCID: PMC12993733
Çitilcioğlu, Özdoğan. Perioperative Management of Patients using GLP-1 Receptor Agonists Current Evidence, Risks, and Practical Recommendations-A Narrative Review. Turkish Journal of Anaesthesiology and Reanimation. 2026. PMID: 42332931 PMCID: PMC13308581
Quick Answers
How is multi-organ endometriosis treated without organ removal?
In many multi-organ cases, the goal is conservative surgery: removing endometriosis while preserving the organs themselves. That typically means meticulous excision of disease from surfaces and deeper planes around the bowel, bladder, ureters, ovaries, and pelvic sidewalls—freeing organs from scar tissue and restoring normal anatomy without taking the organ out. Because endometriosis can hide in distorted or “frozen” anatomy, the safest way to preserve organs is often a highly precise approach that can dissect around vital structures.
In our practice, we use robotic excision to improve visualization and fine-control dissection, which is especially helpful when disease involves multiple compartments or has been operated on before. When endometriosis is close to structures like the ureters, bowel, diaphragm, or certain nerves, treatment planning may include coordinated work with other surgical specialists so the disease can be fully addressed in one operation while still prioritizing organ-sparing techniques.
Organ removal is usually considered only when an organ is severely damaged, there are multiple large endometriomas that can’t be safely managed with tissue-sparing techniques, fertility-safety concerns arise (like a badly damaged tube), or there’s concern for tumor or malignant change. If you’re trying to avoid organ removal, we can help map likely disease sites, clarify your priorities (pain relief, function, fertility), and outline what organ-preserving excision could realistically look like in your specific case—then build a surgical plan around that.
How much time off work do I need after endometriosis surgery?
Most people need about 2–3 weeks off work after minimally invasive endometriosis excision, especially if your job is mainly desk-based and you can ease back in. With robotic excision, patients often go home the same day or next day, start walking comfortably within about a week, and many feel ready for a gradual return to typical daily routines in that 2–3 week window.
The exact time off depends less on the incision size and more on what we need to treat during surgery—for example, ovarian endometriomas, bowel/bladder/ureter involvement, extensive scar tissue (“frozen pelvis”), or additional procedures like appendix removal or adenomyosis-related surgery. More complex, multi-organ cases can mean more fatigue, more activity restrictions, and a higher chance of needing an overnight stay, which can extend the time you’ll want to plan away from work.
In most straightforward recoveries, many patients are back to full activity by about a month. If you tell our team what you do for work (lifting, long shifts, travel, on-your-feet all day vs remote/desk), we can help you plan a realistic time-off request and a safer return-to-work ramp based on the surgical plan we’re building for you.
When is hysterectomy recommended for adenomyosis?
A hysterectomy is typically considered for adenomyosis when symptoms are severe and clearly uterus-driven—most often heavy bleeding (sometimes with anemia), intense cramping, pelvic pressure, and daily quality-of-life disruption—and you’re not planning future pregnancy. It’s the most definitive option because adenomyosis lives within the uterine muscle, so removing the uterus removes the source of the problem.
In practice, we usually weigh hysterectomy most strongly when conservative options haven’t brought acceptable relief, aren’t tolerated, or don’t fit your goals. The decision also depends on the pattern and extent of disease (diffuse adenomyosis versus a more focal adenomyoma that may be removable while preserving the uterus) and whether endometriosis may also be present. If endometriosis is part of the picture, it’s important to know that hysterectomy alone doesn’t treat disease outside the uterus—durable symptom relief depends on addressing all pain generators.
If you’re wondering whether you’re at the point where hysterectomy makes sense, our team can help clarify what’s most likely driving your symptoms, review imaging, and walk you through uterus-preserving versus definitive surgical paths so you can choose the option that best matches your relief and fertility priorities.
What is deep infiltrating endometriosis (DIE) and how is it treated?
Deep infiltrating endometriosis (DIE) is endometriosis that grows deeper into tissue—often described as more than ~5 mm below the surface—and it commonly involves structures like the uterosacral ligaments, rectovaginal space, bowel, bladder, or ureters. Because it can inflame, scar, tether, or even narrow/obstruct nearby organs, DIE may show up as “non-gynecologic” symptoms such as bowel or urinary pain, painful sex, nerve-type pelvic pain, or symptoms that don’t match a routine pelvic exam.
Treatment depends on where the disease is and what it’s affecting, but DIE is the subtype most likely to require specialized surgical planning. When surgery is appropriate, meticulous excision (removing disease at its roots rather than burning the surface) is the gold-standard approach for durable symptom relief and for addressing organ involvement; in complex cases this can include careful work around the bowel, bladder, and ureters. Our team focuses on advanced, precision excision (often using robotic technology) with a tailored plan that prioritizes safety, completeness, and your goals—whether that’s pain relief, fertility, or protecting organ function.
Because DIE can be missed on basic exams and even “normal” imaging, evaluation often requires a higher index of suspicion and the right strategy for mapping disease before any procedure. If DIE sounds like it could explain your symptoms, explore our detailed resources on deep disease and excision, or reach out to schedule a consultation so we can review your history, imaging, and next steps together.
What should I ask at an adenomyosis surgery consult?
At an adenomyosis surgery consult, we want you to leave with clarity on the goal of treatment—are we primarily trying to control heavy bleeding, relieve pain/pressure, protect fertility, or all three? Ask what is driving your symptoms based on your history and imaging (ultrasound/MRI), and whether adenomyosis seems diffuse versus a more localized adenomyoma, because that often changes what surgery can realistically accomplish. It’s also important to ask how often adenomyosis overlaps with endometriosis in cases like yours and whether your surgical plan accounts for both.
Then get very specific about options and tradeoffs: ask whether a uterus‑preserving approach is feasible for you versus whether hysterectomy is the most definitive path, and what symptom relief you can reasonably expect with each. Ask what the anticipated scope of surgery is (uterus only vs. evaluation/treatment of other pelvic sites), what surgical approach will be used (laparoscopic vs. robotic), and how the team plans to maximize completeness and safety in complex anatomy. Finally, ask about recovery logistics—same‑day vs. overnight stay, typical timeline back to daily activities, and what postoperative follow‑up looks like—so you can plan your life around the procedure; if you’d like, reach out and we can review your records and imaging with you and map a surgical plan aligned with your goals.


